Dr. Diane C Bassham

Walter E. and Helen Parke Loomis Professor of Plant Physiology, Department of Genetics, Development and Cell Biology
Diane BASSHAM photo

My research interests focus on understanding the biogenesis and functions of the plant vacuole. The vacuole is a large organelle that has diverse roles in maintenance of turgor, storage of proteins, ions and metabolites, and degradation of proteins and other macromolecules. A major research project in my lab involves the study of vacuolar autophagy, a pathway for uptake of proteins into the vacuole for degradation during environmental stress and senescence. Plants defective in this pathway are more sensitive to stress conditions and show premature leaf senescence. A second project is the analysis of the vesicle trafficking pathway delivering newly-synthesized proteins to the vacuole. Both projects involve cell and molecular approaches combined with genetic analyses to determine the function of individual proteins in the respective pathways.


Integrated and Dynamic Multi-Spectroscopic in situ Imaging of Plant Metabolism at the Level of Subcellular Compartments

Area of Expertise: 
Plant Cell Biology
B.Sc., Biochemistry, First Class (Honours), University of Birmingham, England
Ph.D., Biological Sciences, University of Warwick, England
1035B Carver Co-Lab